Department of Radiology
Found 40 results
Filters: Author is Gabr, Moustafa T  [Clear All Filters]
2023
Abdel-Rahman SA, Zhang L, Gabr MT.  2023.  Development of a high-throughput TR-FRET screening assay for LAG-3/FGL1 interaction.. SLAS Discov. 28(4):188-192.
Abdel-Rahman SA, Rehman AUr, Gabr MT.  2023.  Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3).. ACS Med Chem Lett. 14(5):629-635.
Calvo-Barreiro L, Talagayev V, Pach S, Abdel-Rahman SA, Wolber G, Gabr MT.  2023.  Discovery of ICOS-Targeted Small Molecules Using Pharmacophore-Based Screening.. ChemMedChem. 18(23):e202300305.
Manzoor S, Gabr MT, Nafie MS, Raza MKausar, Khan A, Nayeem SM, Arafa RK, Hoda N.  2023.  Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy.. ACS Chem Neurosci.
Abdel-Rahman SA, Talagayev V, Pach S, Wolber G, Gabr MT.  2023.  Discovery of Small-Molecule TIM-3 Inhibitors for Acute Myeloid Leukemia Using Pharmacophore-Based Virtual Screening.. J Med Chem. 66(16):11464-11475.
Abdel-Rahman SA, Świderek K, Gabr MT.  2023.  First-in-class small molecule inhibitors of ICOS/ICOSL interaction as a novel class of immunomodulators.. RSC Med Chem. 14(9):1767-1777.
Madhav H, Abdel-Rahman SA, Hashmi MAmiruddin, Rahman MAtaur, Rehan M, Pal K, Nayeem SM, Gabr MT, Hoda N.  2023.  Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization.. Eur J Med Chem. 254:115354.
2022
Abdelrahman SA, Gabr MT.  2022.  Emerging small-molecule therapeutic approaches for Alzheimer's disease and Parkinson's disease based on targeting microRNAs.. Neural Regen Res. 17(2):336-337.
Elgakhow AK, Hagag RY, Soliman GA, Gabr MT.  2022.  Prevalence of Chronic Kidney Disease in Nonalcoholic Fatty Liver Disease Patients.. Saudi J Kidney Dis Transpl. 33(1):201-209.
2021
Manzoor S, Prajapati SKumar, Majumdar S, Raza MKausar, Gabr MT, Kumar S, Pal K, Rashid H, Kumar S, Krishnamurthy S et al..  2021.  Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.. Eur J Med Chem. 215:113224.
Manzoor S, Gabr MT, Rasool B, Pal K, Hoda N.  2021.  Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease.. Bioorg Chem. 116:105354.
Rehman AUr, Zhen G, Zhong B, Ni D, Li J, Nasir A, Gabr MT, Rafiq H, Wadood A, Lu S et al..  2021.  Mechanism of zinc ejection by disulfiram in nonstructural protein 5A.. Phys Chem Chem Phys. 23(21):12204-12215.
Gabr MT, Deganutti G, Reynolds CA.  2021.  Peptidomimetic-based approach toward inhibitors of microbial trimethylamine lyases.. Chem Biol Drug Des. 97(2):231-236.
2020
Gabr MT, Machalz D, Pach S, Wolber G.  2020.  A benzoxazole derivative as an inhibitor of anaerobic choline metabolism by human gut microbiota.. RSC Med Chem. 11(12):1402-1412.
Gabr MT, Gambhir SS.  2020.  Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA).. J Am Chem Soc. 142(38):16194-16198.
Gabr MT, Peccati F.  2020.  Dual Targeting of Monomeric Tau and α-Synuclein Aggregation: A New Multitarget Therapeutic Strategy for Neurodegeneration.. ACS Chem Neurosci. 11(14):2051-2057.
Gabr MT, Barbault F.  2020.  First dual binder of microRNA-146a and monomeric tau: a novel approach for multitargeted therapeutics for neurodegenerative diseases.. Chem Commun (Camb). 56(67):9695-9698.
Gabr MT, Balupuri A, Kang NSook.  2020.  High-Throughput Platform for Real-Time Monitoring of ATP-Generating Enzymes in Living Cells Based on a Lanthanide Probe.. ACS Sens. 5(7):1872-1876.
Gabr MT, Brogi S.  2020.  MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis.. J Med Chem. 63(17):9695-9704.
Wardak M, Gowrishankar G, Zhao X, Liu Y, Chang E, Namavari M, Haywood T, Gabr MT, Neofytou E, Chour T et al..  2020.  Molecular Imaging of Infective Endocarditis With 6''-[F]Fluoromaltotriose Positron Emission Tomography-Computed Tomography.. Circulation. 141(21):1729-1731.
Maramai S, Benchekroun M, Gabr MT, Yahiaoui S.  2020.  Multitarget Therapeutic Strategies for Alzheimer's Disease: Review on Emerging Target Combinations.. Biomed Res Int. 2020:5120230.
Gabr MT, Yahiaoui S.  2020.  Multitarget Therapeutics for Neurodegenerative Diseases.. Biomed Res Int. 2020:6532827.
Gabr MT, Haywood T, Gowrishankar G, Srinivasan A, Gambhir SS.  2020.  New synthesis of 6″-[ F]fluoromaltotriose for positron emission tomography imaging of bacterial infection.. J Labelled Comp Radiopharm. 63(11):466-475.
2019
Gabr MT, F Pigge C.  2019.  Expanding the Toolbox for Label-Free Enzyme Assays: A Dinuclear Platinum(II) Complex/DNA Ensemble with Switchable Near-IR Emission.. Molecules. 24(23)
Ibrahim MM, Gabr MT.  2019.  Multitarget therapeutic strategies for Alzheimer's disease.. Neural Regen Res. 14(3):437-440.