DICI Resources
The Dalio Institute for Cardiovascular Imaging (Dalio) is dedicated to multidisciplinary research, education and innovation in cardiovascular imaging and the prevention, diagnosis and treatment of cardiovascular diseases. Dalio is comprised of cardiologists, scientists with expertise in clinical trials and epidemiology, biomedical and electrical engineers, machine- learning engineers, computer-science engineers specializing in machine learning, computer vision, and software development, as well as biostatisticians, imaging technologists, and experienced research coordinators. Dalio benefits immensely from an intellectually rich environment where people across disciplines can closely collaborate.
Dalio encompasses approximately 3,000 square feet dedicated to patient-oriented clinical research in cardiovascular imaging, prevention, diagnosis and therapeutics, and 2,500 square feet dedicated to engineering research in 3D printing, in-vitro flow circulation, biomechanics and material testing.
There are multiple Digital Imaging and Communications in Medicine (DICOM) viewing workstations available for image analysis in a dedicated laboratory including General Electric (GE) AW Server 30,000 Images, with thin client technology, and local and remote 3D visualization (GE Healthcare, Waukesha, WI), GE Advantage Workstations (GE Healthcare, Waukesha, WI), Osirix MD Workstation (Pixmeo, Geneva, Switzerland), QAngio CT RE (Medis Specials, Leiden, NL), and a QAngio XA (Medis Specials, Leiden, NL).
Dalio, which regularly invites leading researchers from around the world to present at monthly Grand Rounds, is equipped with high-end computers offering the latest office, image analysis, computer-aided design, computer-aided engineering and statistical software, as well as high-speed gigabyte network connections; printers, digital scanners, copy and fax machines; telephone conferencing capability; 32 terabytes of encrypted media storage with redundant back-up storage for all data. Dalio has access to multiple conference rooms with state-of-the-art audio-visual and video-conferencing equipment. To provide a secure environment for materials and sensitive data, Dalio offices have restricted access and are equipped with locked cabinets. In addition to local media storage solutions, Dalio has access to more than 1O terabytes of additional expandable network storage with off-site data backup, as well as data integration within a dedicated research picture archiving and communication system (PACS). Multiple DICOM viewing workstations available for image analysis in a dedicated laboratory include 12 GE Advantage Workstations (GE Healthcare, Waukesha, Wl), 1 Osirix MD.
Fabrication Equipment:
- 1 Stratasys J826 Multi-material 3D printer
- 1 DLP-based 3D printer
- 1 Extrusion-based 3D printer for liquid materials (custom-built)
- 1 Laser cutter (VLS 2.3)
- 1 Graphtec (GTCE6000-40) cutter plotter
- 1 Spin coater (Laurel)
- 1 Plasma Etch Plasma Cleaner (PE25)
Mixed/Augmented Reality Headsets and Guidance Systems:
- 3 Microsoft Hololens 2
- 1 Microsoft Hololens 1
- 1 XReal Air AR glasses
- 2 NuEyes Pro3 glasses
- 1 LumePad Hologram Tablet
- 1 Ascension trakSTAR 6dof x4 EM trackers
Imaging Equipment:
- 1 Mindray; Portable Ultrasound Imaging System
- 1 Epic CVx Ultrasound Imaging System: L12-3 Probe, X5-1 Probe, Verisight Pro Probe
Soft Materials Characterization and Processing:
- 1 TA Instruments BioDynamic 5100, Mechanical Stimulation Bioreactor
- 1 Micro-epsilon; Digital Micrometer
- 1 Tensile/compression testing system (Instron 5943)
- 1 BelArt Product; Vacuum desiccator for infiltration1 Vacuum desiccator for self-assembled monolayer treatment
- 1 Vacuum desiccator for self-assembled monolayer treatment
- 5 Ovens (VWR)
- 3 Chemical fume hoods
- 1 UVP; CL-1000 Ultraviolet Crosslinker
Cleanroom Facility (300 sq. ft. class 1000):
- 1 Photolithography (MJB 3 mask aligner)
- 1 Spin coater (Headway research)
- 1 Reactive Ion Etching (Oxford 80 plus)
- 1 Physical Vapor Deposition (AJA ATC-2030 e-beam evaporator)
- 1 Wet chemical acid station
- 1 Wet chemical lithography station
- Ultrasonic bath
Electronics Characterization:
- 1 JSR; Ultrasonic, DPR300 Pulser/Receiver with Transducers
- 1 Probe station (Signatone)
- 1 Semiconductor parameter analyzer (Keithley 4200)
- 2 DC power supply (Keithley)
- 2 Function generator (Keithley)
- 1 Oscilloscope (Keithley)
- 1 High voltage power supply (TREK 2020)
- 1 NDI; Model 130, EM sensor 3D position tracker system
- 1 Hioki; 3506-10, Capacitance meter
- 1 Sparkfun Electronics; 303D, SMD rework station
Cell Culture:
- 1 6’ biosafety cabinet
- 2 Incubators (temperature and humidity control)
- 1 Autoclave
- 1 Waterbath
- 1 Centrifuge
- 1 Microcentrifuge
Optical/Analytical Tools:
- 1 Dantec Dynamics; Time-Resolved Particle Image Velocimetry system
- 1 Mindray; Portable Ultrasound Imaging
- 1 FLIR A325; Thermal camera
- 1 Confocal microscope (Zeiss LSM 700)
- 1 Stereoscope (Zeiss Stemi 2000)
- 1 Inverted routine microscope (Zeiss Primo Vert)
- 1 Inverted slide microscope (Zeiss Primo Star)
- 1 Multimode Microplate Reader (SpectraMax M2e)
- 1 Analytical Balance
- 1 pH meter