MIf-PET: motion-tracked immersive functional positron emission tomography for behavioral neuroscience
The XEIL Lab has developed a novel technological platform called Motion-tracked Immersive functional Positron Emission Tomography (MIf-PET) with high temporal and spatial resolution (i.e., ∼ 1 s frame time interval and ∼ 1 mm resolution) for multimodal brain stimulation and multimodal quantification of complex behavior. Brain stimulation using the controlled life-like augmented reality (AR)...
Inverse Rendering (IR) for high-resolution PET image reconstruction
The XEIL Lab has developed a new high-resolution image reconstruction framework based on a physically-based differentiable rendering of the emission image, which aims to produce the highest-resolution PET images due to accurate Monte Carlo (MC)-based forward modeling of the imaging system. We will use a differentiable objective function and apply a gradient-based optimization method in the...
HiRAP-PCM: high resolution arbitrary path photon counting mammography for single exposure contrast enhanced breast imaging
XEIL Lab has developed a prototype High-Resolution Arbitrary Path Photon Counting Mammography (HiRAP-PCM) scanner. This platform employs photon-counting (PC) technology (55-micron meter pixels with CdTe detectors) and robotic arms to perform mammography along arbitrary trajectories in 3D space, improving image quality while reducing patient radiation exposure. The HiRAP-PCM system offers high...
Prism-PET: A TOF-DOI-Compton PET detector technology for total-body PET imaging
The large axial field-of-view PET scanners, such as the United Imaging EXPLORER and the Siemens Biograph Vision Quadra, can experience severe image blur due to parallax artifacts. In this funded R01 grant, the XEIL Lab will address this via depth encoding by developing practical single-ended PET detector modules with depth-of-interaction localization using our novel right-angle prism mirror light...
Prism-PET/EMMT: high Resolution, cost-effective, portable, and upright brain PET scanner for early diagnosis of alzheimer's disease
The major goals of this funded U01 grant are:1.) Develop a compact, portable, cost-effective, and upright brain PET scanner — known as Prism-PET — with ultra-high resolution, high sensitivity, motion compensation, and CT-less attenuation correction.2.) Integrate the Prism-PET brain scanner with our ultra-high resolution electromagnetic motion tracking (EMMT) to eliminate motion artifacts.3.)...