XEIL Lab has developed a prototype High-Resolution Arbitrary Path Photon Counting Mammography (HiRAP-PCM) scanner. This platform employs photon-counting (PC) technology (55-micron meter pixels with CdTe detectors) and robotic arms to perform mammography along arbitrary trajectories in 3D space, improving image quality while reducing patient radiation exposure. The HiRAP-PCM system offers high flexibility in imaging, allowing clinicians to capture 2D and 3D images from various angles with high spatial resolution, thereby improving the detection of small, inconspicuous lesions. In preliminary tests with the BR3D phantom, the HiRAP-PCM system successfully resolved fine details of the phantom, including fibers as small as 0.15 mm, specks at 0.165 mm, and 1.8 mm spheroidal masses in 2D mammography. These results significantly improve current clinical mammography systems, which typically only resolve larger structures of >3 mm. Furthermore, the system employs laser distance mapping to optimize the alignment of the robot arms, and it could be integrated with the inverse-rendering-based 3D reconstruction techniques, which can further enhance the imaging resolution. These advancements make HiRAP-PCM a promising early breast cancer imaging and diagnosis tool. Researchers are also adapting the HiRAP-PCM technology for head and neck imaging, leading to the development of the High-Resolution Arbitrary Path Photon Counting Computed Tomography (HiRAP-PCCT) system. HiRAP-PCCT is particularly effective in detecting carotid artery disease. Its higher spatial resolution helps reduce the partial volume effects, while the multiple energy window of the PC technique enables the material decomposition of plaques. This allows for precise evaluation of luminal stenosis and accurate identification of vulnerable plaques, such as microcalcifications and spotty calcifications, which are often missed by traditional CT systems due to limited spatial resolution.