The XEIL Lab has developed a novel technological platform called Motion-tracked Immersive functional Positron Emission Tomography (MIf-PET) with high temporal and spatial resolution (i.e., ∼ 1 s frame time interval and ∼ 1 mm resolution) for multimodal brain stimulation and multimodal quantification of complex behavior. Brain stimulation using the controlled life-like augmented reality (AR) environment and its high ecological validity enables us to conduct novel behavioral paradigms. MIf-PET aims to enable the synchronization of immersive behavioral tasks with in vivo high-resolution brain imaging in a more naturalistic sitting position without head confinement to understand functional neural activity better. The wearable AR-based brain stimulation with real-time eye tracking is ambulatory. It can be done at home to capture oculomotor behavior over a much longer time period than is possible at a hospital.