Cancerous tissue surgical resection is a critical procedure for solid tumor treatment. During the operation, the surgeon primarily identifies the cancerous tissues by naked-eye visualization under white light; therefore, the outcome heavily relies on the surgeon’s experience. CypH-11, a near-infrared pH-responsive fluorogenic dye, was developed to delineate the tumor margin in real-time for surgical guidance. The Tung lab enables the “spray-and-see” concept by the fluorogenic property and near-instant signal development capability.
On Oct. 13, 2021, the American Chemical Society (ACS) Weekly PressPac highlighted this advance from the Tung lab in the article, “Fluorescent spray lights up tumors for easy detection during surgery.”
Publication: Near-infrared fluorogenic spray for rapid tumor sensing, ACS Sensors: 2021, 6, 3657-3666. PMID: 34549942.