Title | Regional analysis of femoral head perfusion following displaced fractures of the femoral neck. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Dyke JP, Lazaro LE, Hettrich CM, Hentel KD, Helfet DL, Lorich DG |
Journal | J Magn Reson Imaging |
Volume | 41 |
Issue | 2 |
Pagination | 550-4 |
Date Published | 2015 Feb |
ISSN | 1522-2586 |
Keywords | Adult, Aged, Aged, 80 and over, Contrast Media, Female, Femoral Neck Fractures, Femur Head, Gadolinium DTPA, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Middle Aged, Prospective Studies |
Abstract | PURPOSE: To assess regional variations in the arterial and venous blood supply to the femoral head following displaced fracture of the femoral neck using dynamic contrast enhanced (DCE)-MRI quadrant analysis. MATERIALS AND METHODS: A total of 27 subjects with displaced femoral neck fractures were enrolled in the study. Quadrant specific DCE-MRI perfusion analysis was performed on a 1.5 Tesla MRI scanner. Simultaneous imaging of control and displaced fractured hips was done for comparison. RESULTS: Quadrant specific decreases were found in the arterial (A (0.52 versus 0.27; P = 5.7E-13), Akep (1.0/min(-1) versus 0.41/min(-1) ; P = 1.3E-9) and venous (kel (0.05/min(-1) versus -0.02/min(-1) ; P = 5.1E-5) supply to the femoral head between control and injured sides using a two-factor analysis of variance test. The fractional perfusion (initial area under the curve) in the supero/inferolateral quadrants was 49% min/54% min, in the supero/inferomedial quadrants was 43% min/46% min and for the total femoral head was 39% min on the fracture versus control sides. CONCLUSION: Quadrant specific decreases in arterial and venous perfusion on the fracture side were observed when compared with control. |
DOI | 10.1002/jmri.24524 |
Alternate Journal | J Magn Reson Imaging |
PubMed ID | 24338938 |
Related Institute:
MRI Research Institute (MRIRI)