Long-axial field-of-view PET

Completed Research Project
Investigator(s): 
Sadek Nehmeh, Ph.D.
Last Updated: 
June 14, 2022

Positron emission tomography (PET) sensitivity and applications (in particular those requiring simultaneous imaging of distant organs) are hindered due to the scanner limited axial field-of-view (AFOV), typically <26cm. A longer AFOV will create new opportunities to extend PET clinical and research applications to perform studies that benefit from simultaneous imaging of distant organs, such as simultaneous multi-organs kinetic modeling, and imaging of multi-system diseases. 

Recent data from the world-first 2m long total-body PET, μEXPLORERTM (United Imaging, China), are breathtaking and confirm the great impact that a long AFOV will have on future PET applications. However, the dramatic increase in cost due to the large number of detectors required to cover the long axial FOV will remain a major limitation for the worldwide dissemination of such technology.  

Sparse detector configuration offers a potential cost-effective solution to extending the axial scanner field-of-view. In recent work, using Monte Carlo simulations, the Nehmeh group showed the feasibility of carrying out PET imaging with only 50% of the detectors enclosed in a PET tomograph, and without impacting corresponding image quality. 

Collaborators

Nikolaos (Nicolas) A. Karakatsanis, Ph.D.

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065 Phone: (212) 746-6000