Acute genetic manipulation of phosphoinositide metabolism to rescue lipid and behavioral deficits in AD mouse model

Active Research Project
Laura Beth McIntire, Ph.D.
Last Updated: 
April 14, 2022

Using optogenetics to temporally and spatially regulate phosphoinositide lipid synthesis in the mouse brain, the McIntire lab has shown amelioration of phosphoinositide dysregulation and behavioral benefit in a mouse model of Alzheimer's disease (AD). 

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065