| Title | Sugar sensing based on induced pH changes. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Kim Y, Hilderbrand SA, Weissleder R, Tung C-H |
| Journal | Chem Commun (Camb) |
| Issue | 22 |
| Pagination | 2299-301 |
| Date Published | 2007 Jun 14 |
| ISSN | 1359-7345 |
| Keywords | Absorption, Biosensing Techniques, Boronic Acids, Carbohydrates, Fluorescent Dyes, Hydrocarbons, Aromatic, Hydrogen-Ion Concentration, Infrared Rays, Solubility, Spectrometry, Fluorescence, Water |
| Abstract | A sensory assembly consisting of a pH sensitive NIR dye and an arylboronic acid shows ratiometric absorption changes with increased fluorescence intensity upon addition of sugar in aqueous media; this demonstrates a new signal transduction mechanism for the detection of sugar based on pH changes induced in the microenvironment of the sensory assembly. |
| DOI | 10.1039/b700741h |
| Alternate Journal | Chem Commun (Camb) |
| PubMed ID | 17534523 |
| Grant List | P50-CA86355 / CA / NCI NIH HHS / United States R01 CA099385 / CA / NCI NIH HHS / United States R33 CA114149 / CA / NCI NIH HHS / United States |
Related Institute:
Molecular Imaging Innovations Institute (MI3)