Reliability and agreement of sodium (Na) MRI in calf muscle and skin of healthy subjects from the US.

TitleReliability and agreement of sodium (Na) MRI in calf muscle and skin of healthy subjects from the US.
Publication TypeJournal Article
Year of Publication2018
AuthorsDyke JP, Meyring-Wösten A, Zhao Y, Linz P, Thijssen S, Kotanko P
JournalClin Imaging
Volume52
Pagination100-105
Date Published2018 Nov - Dec
ISSN1873-4499
KeywordsAdult, Aged, Female, Healthy Volunteers, Humans, Leg, Magnetic Resonance Imaging, Male, Middle Aged, Muscle, Skeletal, Reproducibility of Results, Skin, Sodium, Young Adult
Abstract

PURPOSE: To quantify the reliability and agreement of sodium (Na) MRI in calf muscle and skin of healthy subjects and to measure the smallest real difference (SRD) in each.

SUBJECTS AND METHODS: Thirty healthy subjects underwent Na MRI studies of the calf. A scan-rescan protocol was performed the same day and 1 week later. Relative sodium concentration was measured in the calf muscle and skin and compared between studies.

RESULTS: A high degree of reliability was confirmed between the scan and rescan tests using linear regression analysis. The Bland-Altman plots indicated high agreement between runs in all regions. The SRD was measured between scans taken the same day and one week later. Correlations were also reported with age, gender and race.

CONCLUSIONS: Reliability and agreement of Na MRI in the calf muscle and skin show promise for accurately assessing serial changes in patients.

DOI10.1016/j.clinimag.2018.07.010
Alternate JournalClin Imaging
PubMed ID30041116
Related Institute: 
MRI Research Institute (MRIRI)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065