| Title | Layer-by-layer construction of an oxygen-generating photo-responsive nanomedicine for enhanced photothermal and photodynamic combination therapy. |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Du B, Zhang W, Tung C-H |
| Journal | Chem Commun (Camb) |
| Volume | 55 |
| Issue | 42 |
| Pagination | 5926-5929 |
| Date Published | 2019 May 25 |
| ISSN | 1364-548X |
| Keywords | Cell Line, Tumor, Humans, Lysosomes, Nanomedicine, Oxygen, Photochemotherapy, Photosensitizing Agents |
| Abstract | A multifunctional photosensitive and photothermal nanomedicine, AMP-Ce6-HA, was prepared by sequentially layering hard and soft functional molecules. AMP-Ce6-HA was efficiently picked up by MDA-MB-231 breast cancer cells, and then released oxygen in lysosomes. The photothermal and oxygen-enhanced photodynamic combination therapy was much more effective than the single one. |
| DOI | 10.1039/c9cc01461f |
| Alternate Journal | Chem Commun (Camb) |
| PubMed ID | 31049497 |
Related Institute:
Molecular Imaging Innovations Institute (MI3)