| Title | The hippocampus in aging and Alzheimer's disease. |
| Publication Type | Journal Article |
| Year of Publication | 1995 |
| Authors | de Leon MJ, Convit A, DeSanti S, Golomb J, Tarshish C, Rusinek H, Bobinski M, Ince C, Miller DC, Wisniewski HM |
| Journal | Neuroimaging Clin N Am |
| Volume | 5 |
| Issue | 1 |
| Pagination | 1-17 |
| Date Published | 1995 Feb |
| ISSN | 1052-5149 |
| Keywords | Aged, Aged, 80 and over, Aging, Alzheimer Disease, Atrophy, Dementia, Diagnosis, Differential, Diagnostic Imaging, Hippocampus, Humans, Parkinson Disease, Putamen |
| Abstract | The role of imaging in the evaluation of neurodegenerative disorders is summarized. The primary role of imaging is to exclude potentially treatable disorders such as meningioma, extracerebral hematoma, Wernicke's disease, and hypothyroidism. Atrophic changes dominate in the hippocampal region on Alzheimer's disease versus the anterior, frontal, and temporal lobes in Pick's disease. Signal hypointensity in the putamen on T2-weighted spin-echo images favors poorly drug-responsive Parkinson's disease whereas putaminal hyperintensity is observed with Creutzfeldt-Jacob, Wilson's, and Leigh's diseases. As our population ages, a thorough understanding of imaging findings in a geriatric population assumes an increasing importance. |
| Alternate Journal | Neuroimaging Clin N Am |
| PubMed ID | 7743078 |
| Grant List | P01 AG04220 / AG / NIA NIH HHS / United States P30 AG08051 / AG / NIA NIH HHS / United States R01 AG12101 / AG / NIA NIH HHS / United States |
Related Institute:
Brain Health Imaging Institute (BHII)