Title | Coherence enhancement in quantitative susceptibility mapping by means of anisotropic weighting in morphology enabled dipole inversion. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Kee Y, Cho J, Deh K, Liu Z, Spincemaille P, Wang Y |
Journal | Magn Reson Med |
Volume | 79 |
Issue | 2 |
Pagination | 1172-1180 |
Date Published | 2018 02 |
ISSN | 1522-2594 |
Keywords | Algorithms, Anisotropy, Brain, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging |
Abstract | PURPOSE: To investigate an anisotropic structural prior in morphology enabled dipole inversion (MEDI) for improving accuracy in quantitative susceptibility mapping (QSM). THEORY AND METHODS: Anisotropic weighting (AW) was devised and implemented to incorporate orientation information into the edge agreement in the MEDI method. AW performance was compared with isotropic weighting by testing and validating on in vivo brain multiple orientation MRI data using COSMOS and the (33) component of the susceptibility tensor as reference. RESULTS: Suppressing streaking artifacts, AW improved not only QSM image quality but also accuracy in terms of RMSE (root mean square error), HFEN (high frequency error norm), SSIM (structural similarity index), and GDA (gradient direction agreement). In addition, it outperformed isotropic weighting in region of interest-based analysis. From a computational perspective, AW was as fast as isotropic weighting, taking approximately the same central processing unit times. CONCLUSION: Using AW in MEDI improves QSM accuracy compared with isotropic weighting. Magn Reson Med 79:1172-1180, 2018. © 2017 International Society for Magnetic Resonance in Medicine. |
DOI | 10.1002/mrm.26748 |
Alternate Journal | Magn Reson Med |
PubMed ID | 28556244 |
Grant List | R01 CA181566 / CA / NCI NIH HHS / United States R01 NS090464 / NS / NINDS NIH HHS / United States R01 NS095562 / NS / NINDS NIH HHS / United States S10 OD021782 / OD / NIH HHS / United States |
Related Institute:
MRI Research Institute (MRIRI)