| Title | Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain. |
| Publication Type | Journal Article |
| Year of Publication | 1994 |
| Authors | Davis D, Ulatowski J, Eleff S, Izuta M, Mori S, Shungu D, van Zijl PC |
| Journal | Magn Reson Med |
| Volume | 31 |
| Issue | 4 |
| Pagination | 454-60 |
| Date Published | 1994 Apr |
| ISSN | 0740-3194 |
| Keywords | Animals, Body Water, Brain, Brain Ischemia, Cats, Diffusion, Magnetic Resonance Spectroscopy, Monitoring, Physiologic, Rats |
| Abstract | Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10-s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis. |
| DOI | 10.1002/mrm.1910310416 |
| Alternate Journal | Magn Reson Med |
| PubMed ID | 8208123 |
| Grant List | NINDS NS31490 / NS / NINDS NIH HHS / United States |
Related Institute:
MRI Research Institute (MRIRI)