Department of Radiology
Found 16 results
Filters: Keyword is Plaque, Amyloid  [Clear All Filters]
2016
Yang Y, Wang X, Yang H, Fu H, Zhang J, Zhang X, Dai J, Zhang Z, Lin C, Guo Y et al..  2016.  Synthesis and Monkey-PET Study of (R)- and (S)-F-Labeled 2-Arylbenzoheterocyclic Derivatives as Amyloid Probes with Distinctive in Vivo Kinetics.. Mol Pharm. 13(11):3852-3863.
2015
Yang Y, Zhang X, Cui M, Zhang J, Guo Z, Li Y, Zhang X, Dai J, Liu B.  2015.  Preliminary Characterization and In Vivo Studies of Structurally Identical (18)F- and (125)I-Labeled Benzyloxybenzenes for PET/SPECT Imaging of β-Amyloid Plaques.. Sci Rep. 5:12084.
Yang Y, Fu H, Cui M, Peng C, Liang Z, Dai J, Zhang Z, Lin C, Liu B.  2015.  Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography.. Eur J Med Chem. 104:86-96.
Glodzik L, Rusinek H, Li J, Zhou C, Tsui W, Mosconi L, Li Y, Osorio R, Williams S, Randall C et al..  2015.  Reduced retention of Pittsburgh compound B in white matter lesions.. Eur J Nucl Med Mol Imaging. 42(1):97-102.
2014
Yang Y, Cui M, Zhang X, Dai J, Zhang Z, Lin C, Guo Y, Liu B.  2014.  Radioiodinated benzyloxybenzene derivatives: a class of flexible ligands target to β-amyloid plaques in Alzheimer's brains.. J Med Chem. 57(14):6030-42.
Yang Y, Cui M.  2014.  Radiolabeled bioactive benzoheterocycles for imaging β-amyloid plaques in Alzheimer's disease.. Eur J Med Chem. 87:703-21.
Ishii M, Wang G, Racchumi G, Dyke JP, Iadecola C.  2014.  Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.. J Neurosci. 34(27):9096-106.
2013
Yang Y, Cui M, Jin B, Wang X, Li Z, Yu P, Jia J, Fu H, Jia H, Liu B.  2013.  (99m)Tc-labeled dibenzylideneacetone derivatives as potential SPECT probes for in vivo imaging of β-amyloid plaque.. Eur J Med Chem. 64:90-8.
Wadghiri YZaim, Li J, Wang J, Hoang DMinh, Sun Y, Xu H, Tsui W, Li Y, Boutajangout A, Wang A et al..  2013.  Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging.. PLoS One. 8(2):e57097.
Fu H, Yu L, Cui M, Zhang J, Zhang X, Li Z, Wang X, Jia J, Yang Y, Yu P et al..  2013.  Synthesis and biological evaluation of 18F-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques.. Bioorg Med Chem. 21(13):3708-14.
2012
Cui M, Wang X, Yu P, Zhang J, Li Z, Zhang X, Yang Y, Ono M, Jia H, Saji H et al..  2012.  Synthesis and evaluation of novel ¹⁸F labeled 2-pyridinylbenzoxazole and 2-pyridinylbenzothiazole derivatives as ligands for positron emission tomography (PET) imaging of β-amyloid plaques.. J Med Chem. 55(21):9283-96.
Yu P, Cui M, Wang X, Zhang X, Li Z, Yang Y, Jia J, Zhang J, Ono M, Saji H et al..  2012.  ¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques.. Eur J Med Chem. 57:51-8.
2011
Yang J, Wadghiri YZaim, Hoang DMinh, Tsui W, Sun Y, Chung E, Li Y, Wang A, de Leon M, Wisniewski T.  2011.  Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging.. Neuroimage. 55(4):1600-9.
2008
Sigurdsson EM, Wadghiri YZ, Mosconi L, Blind JA, Knudsen E, Asuni A, Scholtzova H, Tsui WH, Li Y, Sadowski M et al..  2008.  A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice.. Neurobiol Aging. 29(6):836-47.
2006
Blennow K, de Leon MJ, Zetterberg H.  2006.  Alzheimer's disease.. Lancet. 368(9533):387-403.
2001
Wegiel J, Bobinski M, Tarnawski M, Dziewiatkowski J, Popovitch E, Miller DC, Wisniewski T, Golomb J, de Leon MJ, Reisberg B.  2001.  Fibrillar amyloid-beta affects neurofibrillary changes but only in neurons already involved in neurofibrillary degeneration.. Acta Neuropathol. 101(6):585-90.