An investigation to choose the proper therapy technique in the management of autism spectrum disorder.

TitleAn investigation to choose the proper therapy technique in the management of autism spectrum disorder.
Publication TypeJournal Article
Year of Publication2021
AuthorsOzsahin I, Mustapha MT, Albarwary S, Sanlidag B, Ozsahin DUzun, Butler TA
JournalJ Comp Eff Res
Volume10
Issue5
Pagination423-437
Date Published2021 04
ISSN2042-6313
KeywordsAripiprazole, Autism Spectrum Disorder, Fuzzy Logic, Humans, Risperidone
Abstract

Autism spectrum disorder is a class of neurological disorders that affect the development of brain functions. This study aims to evaluate, compare and rank the therapy techniques used in the management of autism spectrum disorder using multicriteria decision-making approaches. Fuzzy PROMETHEE and fuzzy TOPSIS approaches were used. Fuzzy PROMETHEE utilizes a pair-wise comparison of alternatives under the fuzzy environment while fuzzy TOPSIS utilizes geometric distance from the positive ideal solution under the fuzzy environment for the evaluation of the effectiveness of the alternatives.The techniques selected for evaluation are applied behavioral analysis, cognitive behavioral therapy, speech therapy and pharmacological therapy such as Risperidone and Aripiprazole. Criteria used in this study include efficacy, cost and side effects, and their weights are assigned based on specific patient conditions. The results indicate that applied behavioral analysis, cognitive behavioral therapy and speech therapy are the most preferred techniques, followed by Aripiprazole and Risperidone. More criteria could be considered and the weights could be assigned according to the patient profile.

DOI10.2217/cer-2020-0162
Alternate JournalJ Comp Eff Res
PubMed ID33709772
Related Institute: 
Brain Health Imaging Institute (BHII)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065