Early detection of Alzheimer's disease with PET imaging.

TitleEarly detection of Alzheimer's disease with PET imaging.
Publication TypeJournal Article
Year of Publication2010
AuthorsBerti V, Osorio RS, Mosconi L, Li Y, De Santi S, de Leon MJ
JournalNeurodegener Dis
Volume7
Issue1-3
Pagination131-5
Date Published2010
ISSN1660-2862
KeywordsAlzheimer Disease, Fluorodeoxyglucose F18, Humans, Positron-Emission Tomography
Abstract

Preclinical diagnosis of Alzheimer's disease (AD) is one of the major challenges for the prevention of AD. AD biomarkers are needed not only to reveal preclinical pathologic changes, but also to monitor progression and therapeutics. PET neuroimaging can reliably assess aspects of the molecular biology and neuropathology of AD. The aim of this article is to review the use of FDG-PET and amyloid PET imaging in the early detection of AD.

DOI10.1159/000289222
Alternate JournalNeurodegener Dis
PubMed ID20197691
PubMed Central IDPMC3214828
Grant ListP30 AG008051 / AG / NIA NIH HHS / United States
R01 AG013616 / AG / NIA NIH HHS / United States
R01 AG022374 / AG / NIA NIH HHS / United States
Related Institute: 
Brain Health Imaging Institute (BHII)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065