Complete genomic DNA sequence of rock bream iridovirus.

TitleComplete genomic DNA sequence of rock bream iridovirus.
Publication TypeJournal Article
Year of Publication2004
AuthorsDo JWan, Moon CHoon, Kim HJeong, Ko MSeok, Kim SBum, Son JHee, Kim JSoo, An EJeong, Kim MKyoung, Lee SKoo, Han MShin, Cha SJu, Park MSeon, Park MAe, Kim YCheong, Kim JWoo, Park JWoo
JournalVirology
Volume325
Issue2
Pagination351-63
Date Published2004 Aug 01
ISSN0042-6822
KeywordsAnimals, Databases, Protein, DNA Replication, DNA, Viral, Genome, Viral, Iridovirus, Molecular Sequence Data, Perciformes, Phylogeny, Species Specificity, Viral Proteins
Abstract

Iridovirus is a causative agent of epizootics among cultured rock bream (Oplegnathus fasciatus) in Korea. Here, we report the complete genomic sequence of rock bream iridovirus (RBIV). The genome of RBIV was 112080 bp long and contained at least 118 putative open reading frames (ORFs), and its genome organization was similar to that of infectious spleen and kidney necrosis virus (ISKNV). Of the RBIV's 118 ORFs, 85 ORFs showed 60-99% amino acid identity to those of ISKNV. Phylogenetic analysis of major capsid protein (MCP), DNA repair protein RAD2, and DNA polymerase type-B family indicated that RBIV is closely related to red sea bream iridovirus (RSIV), Grouper sleepy disease iridovirus (GSDIV), Dwarf gourami iridovirus (DGIV), and ISKNV. The genome sequence provides useful information concerning the evolution and divergence of iridoviruses in cultured fish.

DOI10.1016/j.virol.2004.05.008
Alternate JournalVirology
PubMed ID15246274
Related Institute: 
Molecular Imaging Innovations Institute (MI3)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065