A Bioluminogenic Probe for Monitoring Tyrosinase Activity.

TitleA Bioluminogenic Probe for Monitoring Tyrosinase Activity.
Publication TypeJournal Article
Year of Publication2017
AuthorsWang J, Lee TSup, Zhang Z, Tung C-H
JournalChem Asian J
Volume12
Issue4
Pagination397-400
Date Published2017 Feb 16
ISSN1861-471X
KeywordsAnimals, Benzaldehydes, Benzothiazoles, Cell Line, Tumor, Firefly Luciferin, Fluorescence, Fluorescent Dyes, Humans, Hydrazones, Mice, Monophenol Monooxygenase
Abstract

A bioluminogenic probe based on luciferin was designed and synthesized to monitor tyrosinase activity. This probe was efficient in assessing tyrosinase activity in a buffered aqueous solution and in measuring endogenous tyrosinase activity in melanoma cells.

DOI10.1002/asia.201601659
Alternate JournalChem Asian J
PubMed ID28052521
Related Institute: 
Molecular Imaging Innovations Institute (MI3)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065