| Title | An acridine amino acid derivative for use in Fmoc peptide synthesis. |
| Publication Type | Journal Article |
| Year of Publication | 1992 |
| Authors | Tung CH, Zhu T, Lackland H, Stein S |
| Journal | Pept Res |
| Volume | 5 |
| Issue | 2 |
| Pagination | 115-8 |
| Date Published | 1992 Mar-Apr |
| ISSN | 1040-5704 |
| Keywords | Acridines, Amino Acid Sequence, Amino Acids, Chromatography, High Pressure Liquid, Fluorenes, Fluorometry, Kinetics, Lysine, Molecular Sequence Data, Molecular Structure, Peptides, Trypsin |
| Abstract | An acridine derivative of N-alpha-Fmoc-lysine has been prepared and used in solid phase peptide synthesis. The fluorescence properties of the acridine reporter group are retained throughout the peptide synthesis procedure. The utility of the acridine group was demonstrated by its use as an energy acceptor in a fluorescence energy-quenching assay with trypsin. |
| Alternate Journal | Pept Res |
| PubMed ID | 1581639 |
Related Institute:
Molecular Imaging Innovations Institute (MI3)