Modulation of arousal regulation with central thalamic deep brain stimulation.

TitleModulation of arousal regulation with central thalamic deep brain stimulation.
Publication TypeJournal Article
Year of Publication2009
AuthorsShah SA, Baker JL, Ryou J-W, Purpura KP, Schiff ND
JournalAnnu Int Conf IEEE Eng Med Biol Soc
Volume2009
Pagination3314-7
Date Published2009
ISSN2375-7477
KeywordsAdult, Animals, Arousal, Attention, Behavior, Behavior, Animal, Brain, Deep Brain Stimulation, Electrophysiology, Humans, Macaca, Male, Memory, Short-Term, Neural Pathways, Neurons
Abstract

To investigate the effects of central thalamic deep brain stimulation (CT/DBS) on behavior and frontal cortical function, we conducted experiments in an awake, behaving macaque monkey performing tasks that required sustained attention and working memory. Results of this preliminary study revealed that CT/DBS can lead to an improvement, a decrement, a mixed or have no effect on behavior.

DOI10.1109/IEMBS.2009.5333751
Alternate JournalAnnu Int Conf IEEE Eng Med Biol Soc
PubMed ID19964301
Related Institute: 
Brain Health Imaging Institute (BHII)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065