Rhenium tricarbonyl complexes of AIE active tetraarylethylene ligands: tuning luminescence properties and HSA-specific binding.

TitleRhenium tricarbonyl complexes of AIE active tetraarylethylene ligands: tuning luminescence properties and HSA-specific binding.
Publication TypeJournal Article
Year of Publication2017
AuthorsGabr MT, F Pigge C
JournalDalton Trans
Volume46
Issue43
Pagination15040-15047
Date Published2017 Nov 07
ISSN1477-9234
KeywordsCoordination Complexes, Crystallography, X-Ray, Humans, Indoles, Ligands, Molecular Conformation, Protein Binding, Rhenium, Serum Albumin, Spectrometry, Fluorescence
Abstract

The synthesis and photophysical properties of luminescent Re(i) tricarbonyl complexes prepared from bis(pyridyl)- and bis(quinolyl) tetraarylethylene (TAE) ligands are reported. Emission wavelengths of the complexes are influenced by structural variation in the tetraarylethylene ligands, and several complexes display aggregation-induced enhanced emission in aqueous solution. A Re(i) complex prepared from an indole-functionalized TAE ligand shows significant enhancement in its luminescence intensity accompanied by a remarkable blue shift (∼95 nm) upon specific binding to site II of human serum albumin.

DOI10.1039/c7dt03380j
Alternate JournalDalton Trans
PubMed ID29063077
Related Institute: 
Molecular Imaging Innovations Institute (MI3)

Weill Cornell Medicine
Department of Radiology
525 East 68th Street New York, NY 10065