
The Moonsoo Jin Lab

Developing CAR T cells for cancer therapy
Near-synchronous imaging of tumor and T cell dynamics reveals tumor and chimeric antigen receptor (CAR) T cell co-localization; CAR T peak after the tumor elimination; and subsequent CAR T egress.

Developing chimeric antigen receptor (CAR) T cells for cancer therapy
Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) sees patient tumors; DOTATATE scans see CAR T cell localization. Phase I study: intercellular adhesion molecule (CAM)-1 targeting CAR T cells and refractory thyroid cancer.

Single cell multiomics
Key tumor-infiltrating (TIL) cells identified via multiomics include immune suppressive regulatory (Treg) and cytotoxic CD8 T cells.

The Jin Lab