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The Molecular Imaging Innovations Institute (MI3) is housed on the top two floors of the Belfer Research Building, which opened in February of 2014. MI3 researchers have full access to 8,000 square feet of laboratory space equipped with the most advanced tools for chemistry, biochemistry, molecular biology, tissue culture, animal handling, and imaging. The laboratories are subdivided into several concentrations.
The chemistry laboratories are specifically designed for the synthesis of novel imaging probes, including all modalities. The laboratory consists of approximately 2,000 sq. ft that is dedicated to nanoparticle preparation and peptide chemistry, and an additional dedicated satellite radiochemistry laboratory. Major equipment include:
Peptide synthesizer (PS3, Protein Technologies)The radiochemistry laboratory located in S-010 has a broad radioisotope license for non-human use including radioisotopes 3H, 11C, 14C, 18F, 32P, 33P, 35S, 46Sc, 51Cr, 59Fe, 64Cu, 67Ga, 68Ga,89Zr, 90Y, 95Nb, 99mTc, 103Ru, 111In, 113Sn, 125I, 141Ce, 153Gd, and 177Lu. The lab is designed for general radiochemistry and radiolabeling of compounds (organic and inorganic). Main equipment include:
This space has been dedicated to molecular biology work, including P-32 and S-35. A Bioassay/Pharmacology laboratory equipped for radioanalytical and biodistribution work is also included within this laboratory.
4,326 sq. ft of laboratory space has been outfitted with the equipment and instruments necessary for performing biochemical assays, purification, and molecular biology. In addition to our standard equipment, the laboratories contain:
